The fiercest public health crisis in a century has elicited cooperative courage and sacrifice across the globe. At the same time, the COVID-19 pandemic is producing severe social, economic, political, and ethical divides, within and between nations. It is reshaping how we engage with each other and how we see the world around us. It urges us to think more deeply on many challenging issues—some of which can perhaps offer opportunities if we handle them well. The transcripts that follow speak to the potency and promise of dialogue. They record two in a continuing series of “COVID-19 In Conversations” hosted by Oxford Prospects and Global Development Institute.